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When I asked Bayley why he published in the Journal of Biological Chemistry in 1987, he replied: "That was sort of the obvious first venue; the one that had a nice circulation at the time." He then confessed that he only wrote the paper to see whether it "stood up" to the rigours of scientific peer review. "It was just a piece of cake," he chuckled. "It was a real piece of cake, in fact."
Bayley was motivated to publish in the Journal of Biological Chemistry because it was a necessary step before moving to Nature when Knowles was appointed as an investigator at Cambridge University, a position he holds today. "Once I was a full professor, it was incumbent on me to publish in Nature in order to demonstrate that I was worthwhile, that I could bring in grants," he remembers.
In getting Bayley's first paper published in 1987, Knowles had done something that's still seldom seen today---a deed that's especially remarkable in view of the fact that he couldn't afford to publish an article for months and was in debt, even before you factor in the costs of printing and postage.
It seems that the journal editors were impressed by his honesty in explaining his difficulties and in providing a direct, contextual account of his work to their readers. "I didn't actually ask for their help," he remembers. "They just let me in; they just let me in. They just said, "Oh, here you are, then. You're trying to do something that ought to be done.” That kind of thing. Eventually, I think I was taken at my word."
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